Post 200 The guide to the region's top businesses

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Employees at HumanGenome Sciences work on manufacturing lupus drug Benlysta. (Jeffrey Macmillan/Capital Business)

Public companies and financial services

Human Genome Sciences

The firm has long been considered one of Maryland’s biotechnology gems. But its first big commercial win came in 2011 when the Food and Drug Administration signed off on Benlysta, the first new drug in 50 years to treat systemic lupus. Sales in the United States have been slow but steady in its first few quarters on the market as the company educates doctors and patients about the product. The company has also dipped its toe into international sales, with many European countries endorsing its use.


In addition to a lupus drug, HGS also has developed a treatment for inhaled anthrax.It is delivering 45,000 doses to the government for a strategic stockpile.

14200 Shady Grove Rd.

Rockville Md., 20850


Founded: 1992

President and CEO: H. Thomas Watkins

Revenue: $157350

Assets: $1315030

Employees (local): 1200 (1100)

NOTE: Our methodology for the rankings.